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RNA Interference
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  RNAi News http://www.rnainews.com
Online resource for scientists, researchers, technologists, and executives engaged in RNA Interference, functional genomics, and drug discovery. Offers industry news, product reviews, and meetings information.
  Cambridge Healthtech Institute http://www.healthtech.com/
CHI organizes RNAi-related conferences throughout the US and Europe, including therapeutics, pharmaceutics, drug development, target discovery, and biodefense. Provides biotechnology news and conferences information.
  A TV Show on RNAi by PBS http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html
NOVA scienceNOW TV program describes RNAi as a major breakthrough in gene therapy with enormous medical promise. Provides basic overview of RNAi technology, current therapeutic approaches, and interview with the experts in the field. Includes 15-minutes TV broadcast segment on RNAi.
  NANOPOLIS http://www.nanopolis.net
Educational portal providing nanotechnology articles and multimedia courses in the multidisciplinary research areas.
  RNAi Mechanism Animation by Journal Nature http://www.nature.com/focus/rnai/animations
An animation from Nature Publishing Group on the mechanism of RNA Interference (RNAi).
  Nuclear Receptor Signaling Atlas http://www.nursa.org/
Informational portal for researchers interested in nuclear receptor signaling.
  Wikipedia Article on RNAi http://en.wikipedia.org/wiki/RNA_interference
Online article describing the basics of RNA Interference (RNAi) mechanism.
  Discovery on Target RNAi meeting http://www.discoveryontarget.com
Annual RNAi meeting hosted by Cambridge Healthcare Institute in Boston, Massachusetts. Meeting provides overview of various aspects in RNA Interference (RNAi) research, ranging from in vitro and in vivo drug discovery research to therapeutic applications. Online meeting information is available: plenary sessions, exhibits, and poster presentations.
  TargetScan http://genes.mit.edu/targetscan/
Online software provided by MIT for prediction of microRNA targets. Provides research data and online software for microRNA target identification and analysis.
  Nature web focus: RNAi http://www.nature.com/nature/focus/rnai/index.html
Online review of RNA Interference biological phenomena. Includes citations of recent research publications, RNAi animations, and science news articles.
  The microRNA Registry http://www.sanger.ac.uk/Software/Rfam/mirna/
Online resource provides a service for the assignment of miRNA gene names. Provides searchable database of published miRNA sequences. Includes data and research application information.
  Ordway Research Institute http://www.ordwayresearch.org
Not-for-profit corporation with a mission to translate basic science observations into therapeutics. Provides research services including quantitation of endogenous levels of microRNAs and mRNAs from experimental samples. Includes information on research focus areas and technology development.
  RNAi Database http://www.rnai.org/
Includes all siRNA from C. elegans including assay, resulting phenotypes, dsRNA target location. Database provides Gene/Protein or Phenotype search options.
  Journal of RNAi and Gene Silencing http://www.libpubmedia.co.uk/RNAiJ/RNAiJHome.htm
Publishes peer-reviewed articles addressing the biology and application of RNA interference and gene silencing. Includes information about journal aims and scope, publication policies, and manuscript submission. Provides online access to journal articles.
  SI RNA - Small Interference RNA Resources http://www.si-rna.com
Online resource from Ion Channel Media Group. Provides news, publication links, and citations of the recent literature relevant to RNA Interference research.
  Rosetta Genomics http://www.rosettagenomics.com/
Israel-based microRNA genomics company, develops bioinformatic tools for miRNA gene detection approach.
  RNAi.net http://www.rnai.net
Online resource offering information RNA interference and related issues: news, interviews, articles, techniques.
  RNAi Resource at Ambion http://www.ambion.com/techlib/resources/RNAi/
Online RNA Interference (RNAi) resource. Provide scientific and technical support, information on microRNA and small interfering RNA application in gene expression research.
  DBTGR - Database of Tunicate Gene Regulation http://dbtgr.hgc.jp
Gene expression database of tunicates. Provides the descriptions of 12 transcription factors and 140 promoters.
  Silencing Genomes http://silencinggenomes.org/
Portal about genome-wide applications of RNAi by Cold Spring Harbor Laboratory.
  Article on siRNA from Wikipedia http://en.wikipedia.org/wiki/Small_interfering_RNA
Describes small interfering RNA (siRNA) function, structure, use in research, and potential application for therapy.
  The RNAi Web http://www.rnaiweb.com/
Online resource for RNA Interference (RNAi) technology. Offers overview of technology, references, and links on other RNAi-related web resources.
  Oligonucleotide Therapeutic Society http://www.myots.org/
Society host conferences on academia and industry-based research and development of oligonucleotide therapeutics: RNAi, antisense, and others. Provides society overview, publication materials, meetings, and contact information.
  The siRNA User Guide http://www.rockefeller.edu/labheads/tuschl/sirna.html
Online guide for performing RNAi experiments using synthetic siRNA molecules. By Tuschl Lab at Rockefeller University.
  MicroRNA in Cancer http://www.nature.com/nature/journal/v435/n7043/edsumm/e050609-16.html
Review of microRNA role in cancer by Nature journal. Provides full-length research papers and reviews.
  RNAi Resource at Macalester College http://www.macalester.edu/~montgomery/RNAi.html
Informational resource, including RNAi mechanism, overview of current studies, and related research protocols.
  The RNAi Cure http://www.pbs.org/wgbh/nova/sciencenow/3210/02-cure.html
A NOVA ScienceNOW science program by PBS feature the possible applications for RNAi therapy. Provides animations of key biological processes and mechanism of RNA Interference.
  RNA Interference at Journal Nature http://www.nature.com/focus/rnai/
Focus RNA Interference - online resource publishing recent advances in RNAi field, and novel applications in Nature Cell Biology and Nature Reviews.
  RNAi@elegansNet http://c.elegans.tripod.com/RNAi.htm
Directory on gene silencing by RNA interference (RNAi) literature and resources.
  Oligoengine http://www.oligoengine.com
Oligonucleotide design software for applications such as RNAi, DNA methylation, antisense, and genome arrays.
  RNAi BioForum http://www.protocol-online.org/forums/index.php?showforum=21
Online forum for siRNA, microRNA and RNAi methods discussion.
  Article on RNAi by GNN http://www.genomenewsnetwork.org/articles/06_02/hiv.shtml
Online article describing gene silencing mechanism and how RNAi can be used for HIV treatment.
  Gene Silencing Mechanism http://www.nature.com/nrg/journal/v2/n2/animation/nrg0201_110a_swf_MEDIA1.html
Animation of post transcriptional gene silencing or RNA Interference (RNAi) by Nature Reviews Genetics.
  Drosophila RNAi Resource http://www.sdbonline.org/fly/aignfam/rnaistuf.htm
Informational RNAi resource on studying drosophila genes and their roles in development by Society for Developmental Biology.
  The MIT/ICBP siRNA Database http://web.mit.edu/sirna/
Online resource for researchers looking for experimentally validated siRNAs and shRNAs against target genes, with a focus on genes thought to be involved in cancer.
  Article on RNAi by HOPES http://www.stanford.edu/group/hopes/treatmts/pbuildup/h2.html
Online article describes basic mechanism of RNAi and how it can be applied for Huntington's disease treatment.
  The RNAi vs. HIV http://myweb.dal.ca/tbaptist/rnai/
Reviews the use of this therapy in fighting HIV. Includes mechanism, difficulties, terms, and featured experiments.
  CnidBase: Cnidarian Evolutionary Genomics Database http://cnidbase.org
Cnidbase provides tools for researchers interested in studying gene expression of these organisms. Provides sequence BLAST tools, keyword search of genes and homologs, a literature scan, and several useful links.
  RNAi Transfection Resource http://cell-transfection.blogspot.com/
Review of transfection techniques such as electroporation, denrimers and lipids that are used for transfection of DNA, RNA, and siRNA. Includes information on optimized cell type specific transfection systems.
  RNAi Gateway http://www.biomedcentral.com/gateways/RNAi/
Web resource from BioMed Central. Provides RNA Interference (RNAi) research highlights, journal links, news, and meeting information.
  microRNA and Cancer Therapeutics http://www.microRNA.ws
Online review of microRNA application for potential therapy of cancer by Dmitriy Ovcharenko.
  siRNA Transfection Resource http://sirnatransfection.org
Cell biology educational resource focused on RNAi and siRNA transfection process. Describes siRNA biological mechanism of action, high-throughput RNAi screens, stable shRNA expression, experimental transfection protocols, and in vivo siRNA applications.
  InFocus RNAi Web Broadcast by Bio.com http://www.bio.com/newsfeatures/infocus.jhtml?infocusId=1200002&realmId=
Review of RNAi advances, technologies and applications. Bio.com provides an online RNAi technology-focused webcast, experts in the field discuss new insights into the regulation of gene expression by RNAi.
  Genetic Diversity http://genetics.nbii.gov
Provides educational modules covering such parts of biology as genetics, cell biology, and gene expression.
  Second Annual Meeting of the Oligonucleotide Therapeutics Society http://www.nyas.org/events/eventDetail.asp?eventID=5753&date=10/19/2006
Yearly conference organized by New York Academy of Sciences. Scientists from industry and academia meet to discuss use of oligonucleotide-based gene-silencing techniques for development of innovative therapeutics. Includes information about conference registration, preliminary program, and abstract submission.
  RNA Interference http://hhmi.org/biointeractive/rna/rnai/
Interactive online resource from Howard Hughes Medical Institute. Presents RNAi mechanism and overview of key scientific findings.
  Transcriptional Gene Silencing http://www.scripps.edu/mem/rheum/morris/tgs/
Mechanisms of TGS by Kevin Morris laboratory. Includes description of HIV research performed using lentiviral vector gene therapy and RNAi mediated gene silencing.
  RNAi Therapeutics: How Likely, How Soon? http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0020028
Review article from PLoS Biology journal. Describes mechanism of RNA Interference, potential applications towards therapeutics, and current problems associated with delivery.
  Navigating Journey of Genome to Medicine http://www.iht.com/articles/2005/06/22/news/snturn.php
Review article on RNAi by International Herald Tribune. Provides an overview on RNA Interference discovery, current research efforts, and therapeutic potential.

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